Surgery for Laryngeal and Hypopharyngeal Cancer

Surgery may be used to treat some laryngeal and hypopharyngeal cancers. Several types of operations can be done, depending on the location and stage of the cancer.

Most experts do not recommend surgery that will totally remove the larynx unless there are no other options.

Surgery for laryngeal and hypopharyngeal cancers is often complex. People tend to have better outcomes if they’re treated at centers that have a lot of experience with head and neck cancers.

Surgery to remove the tumor

In a tumor resection surgery, the entire tumor and a margin (edge) of normal-looking tissue around it are removed (resected). This margin of normal tissue around the tumor is taken out to reduce the chance of any cancer cells being left behind.

The type of surgery you need will depend on the location and size of your tumor.

Endoscopic surgery

For this type of surgery, a scope is passed through your mouth and down your throat to find the tumor. The scope is a long, thin tube with a light and camera on the end. Using the camera, the doctor can see the tumor and pass small surgical tools through the scope to biopsy or remove it.

Because the surgery is done through the mouth, no cuts are needed on the outside of the neck.

Endoscopic surgery is often used to treat some early-stage cancers of the larynx and nearby areas. For some early laryngeal cancers, studies have shown that this can work as well as radiation therapy.

Vocal cord stripping may be used to treat very early cancers of the vocal cords. The doctor removes the top layer of tissue from the vocal cord where abnormal cells are located.

TLM can be used to treat some early-stage cancers of the larynx and hypopharynx. A microscope and a focused laser beam are used to see and remove the tumor very precisely while limiting damage to nearby tissues.

Small robotic instruments controlled by the surgeon are used to remove the tumor with very precise movements. TORS is sometimes used for certain cancers of the larynx or hypopharynx.

Laryngectomy

Laryngectomy is the removal of part or all of the larynx (voice box). It involves making a cut (incision) on the outside of the neck over the area of the Adam’s apple.

Smaller cancers of the larynx can sometimes be treated by removing only part of the voice box. The goal of this surgery is to remove all the cancer while leaving as much of the larynx as possible so speech and swallowing can still work.

Supraglottic laryngectomy

Only the part of the larynx above the vocal cords is removed in this surgery. It may be used to treat some supraglottic cancers. Because the vocal cords are left in place, most people are still able to speak afterward.

Hemilaryngectomy

For some small cancers of the vocal cords, the surgeon may remove only one side of the larynx, including one vocal cord. The other side is left in place. Most people keep some ability to speak after this surgery.

This surgery removes the entire larynx. The trachea (windpipe) is attached to a hole (stoma) made in the skin on the front of the neck. You breathe and cough through this hole instead of through your mouth and nose. It is called a tracheostomy or trach.

If your entire larynx is removed, you will no longer be able to speak as you did before the surgery. But you can learn other ways of speaking through various rehabilitation options after this surgery. See Living as a Laryngeal or Hypopharyngeal Cancer Survivor to learn more.

The connection between the throat and the esophagus (swallowing tube) is usually not affected. You should be able to swallow food and liquids just as you did before the surgery.

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Illustrations by permission of the Mayo Foundation. From “Looking Forward...A Guidebook for the Laryngectomee” by R.L. Keith, et al, New York, Thieme-Stratton, Inc. and copyrighted by the Mayo Foundation, 1984.

Pharyngectomy

Surgery to remove part or all of the pharynx (throat) is called a pharyngectomy. This may be done to treat cancers of the hypopharynx.

  • Partial pharyngectomy: Only the part of the pharynx that contains the cancer is removed in this surgery.
  • Total pharyngectomy: The entire pharynx is removed. The larynx (voice box) is often removed at the same time, especially if the cancer has spread nearby.

After this type of surgery, reconstructive surgery may be needed to rebuild the throat and help improve swallowing.

Thyroidectomy

Sometimes the cancer spreads into the thyroid gland and all or part of it must be removed. Your thyroid sits in the front of your neck and wraps around to the sides of your trachea (windpipe). It makes hormones that control your metabolism and how your body uses calcium.

If all the thyroid gland is removed, your body can no longer make the thyroid hormone it needs. You must take thyroid hormone pills (levothyroxine) to replace the loss of the natural hormone.

Surgery to remove lymph nodes

Cancers of the larynx and hypopharynx can spread to the lymph nodes in the neck. Removing these lymph nodes and other nearby tissues is called a neck dissection or lymph node dissection. It is done at the same time as the surgery to remove the main tumor.

The goal of this surgery is to remove any lymph nodes known to contain cancer. Doctors sometimes recommend an elective lymph node dissection when there is no proof that the cancer has spread to the lymph nodes. This may be done if there is a high chance the cancer has spread to the lymph nodes based on tumor size.

Sentinel lymph node biopsy

In some early-stage laryngeal and hypopharyngeal cancers, a sentinel lymph node biopsy might be done to test the lymph nodes for cancer before removing them. This should only be done at treatment centers by doctors with a lot of experience in the technique.

Types of neck dissection surgery

There are several types of neck dissection procedures. They differ in how much tissue is removed from the neck. The amount of tissue removed depends on the size of the primary cancer and how much it has spread to the lymph nodes.

  • Partial or selective neck dissection: Only a few lymph nodes are removed.
  • Modified radical neck dissection: Most lymph nodes on one side of the neck between the jawbone and collarbone are removed. Some muscle and nerve tissue is also removed.
  • Radical neck dissection: Nearly all nodes on one side are removed, along with even more muscles, nerves, and veins.

Possible side effects

Neck dissection surgery can cause nerve damage. This can lead to numbness of the ear, weakness when raising the arm above the head, and weakness of the lower lip.

Nerves heal slowly, so sometimes these side effects improve over time. If more extensive surgery is needed, the side effects might be permanent. Physical therapy can help improve neck and shoulder movement after any neck dissection surgery.

Reconstructive surgery

If you have extensive surgery to remove your cancer, you may need more surgeries to help restore the parts of your body that were affected.

Reconstructive surgery is not usually needed for small tumors, because the narrow edge of normal tissue removed along with the tumor is usually small. Removing larger tumors may cause changes to your mouth, throat, or neck that need to be repaired.

Skin graft: A thin slice of skin can sometimes be taken from your thigh or another part of your body and used to repair a small area.

Flap surgery: More tissue may be needed to repair a larger area. A piece of muscle with or without skin may be rotated from an area close by, such as the chest (pectoralis major pedicle flap) or upper part of the back (trapezius pedicle flap).

Other surgical options: Due to advances in microvascular surgery (sewing together small blood vessels under a microscope), there are many more options for reconstructing the larynx and hypopharynx. Tissue from other areas of the body, such as the intestine, arm muscle, abdominal (belly) muscle, or lower leg bone, may be used to replace parts of the mouth, throat, or jawbone.

Before you have extensive head and neck surgery, talk to your surgeon about your options for reconstruction.

Surgery to save or restore body function

A tracheostomy is a stoma (hole) made through the skin in the front of the neck and attached to the trachea (windpipe). It is done to help a person breathe.

Short-term tracheostomy

Your doctor may create a short-term tracheostomy if they expect a lot of swelling in your airway after your cancer is removed. This is done by using a small plastic tube to help you breathe more easily until the swelling goes down. It stays in place for a short time and is then removed (reversed) when it's no longer needed.

A short-term tracheostomy may be needed after a partial laryngectomy or pharyngectomy.

Permanent tracheostomy

You may need a permanent tracheostomy if the cancer is blocking your throat and is too big to remove completely. This is a permanent opening to connect a lower part of your windpipe to a stoma (hole) in the front of your neck. It bypasses the tumor and allows you to breathe more comfortably.

A permanent tracheostomy is needed after a total laryngectomy.

Cancer in the larynx or hypopharynx may keep you from swallowing enough food to stay well nourished. This can make you weak and make it harder to complete treatment. Sometimes the treatment itself can make it hard to eat enough. A few different types of feeding tubes might be used in these situations.

Gastrostomy tube (G-tube)

A gastrostomy tube, or G-tube, is a feeding tube put through the skin and muscle of your abdomen (belly) and right into your stomach. Sometimes this tube is placed during a surgery, but often it's put in place through endoscopy.  

When the feeding tube is put in place through endoscopy, it's called a percutaneous endoscopic gastrostomy, or PEG tube.

The tube is placed while you are sedated, using medicine to put you in a deep sleep. The doctor inserts an endoscope down your throat. This is a long, thin and flexible tube with a camera on the end so the doctor can see inside your stomach. The feeding tube is then guided through the endoscope and to the outside of your body.

Once in place, the feeding tube can be used to put liquid nutrition right into your stomach. As long as you can still swallow normally, you can also eat regular food while you have this type of tube.

PEGs can be used for as long as needed. Sometimes these tubes are used for a short time to help keep you healthy and fed during treatment. They can be removed when you are able to eat normally.

Nasogastric feeding tube (NG tube)

If the swallowing problem is likely to be only short-term, another option is a nasogastric feeding tube (NG tube). This tube goes in through your nose, down your esophagus, and into your stomach. Special liquid nutrients are put in through the tube. Some people dislike having a tube coming out of their nose and prefer a PEG tube.

No matter which type of feeding tube you have, you and your caregivers will be taught how to use it. After you leave the hospital, home health nurses may visit to make sure you are comfortable with tube feedings.

If radiation is part of your treatment plan, you must have a dental evaluation before you begin. Depending on the radiation plan and condition of your teeth, some or even all of your teeth may need to be removed before radiation can start.

The teeth may be removed by a head and neck surgeon or an oral surgeon. If broken or infected (abscessed) teeth are left in and exposed to radiation, these teeth are very likely to cause problems such as infections and areas of bone death (necrosis) in the jaw.

Possible risks and side effects of surgery

The risks and side effects of any surgery depend on the extent of the operation and your general health before the surgery. If you are considering surgery, your healthcare team will discuss the likely side effects with you beforehand. Be sure you understand how surgery may affect the way you look and how your body works.

General risks and side effects

All surgery carries some risk, including the possibility of blood clots, bleeding, infections, complications from anesthesia, and pneumonia. These risks are generally low but are higher with more complicated surgeries.

Most people will have some pain for a while after surgery, although this can usually be controlled with medicine. Rarely, some people do not survive surgery.

Impacts of specific surgeries

Laryngectomy, the surgery that removes the voice box, leaves you without the usual means of speech. The voice can be restored in several ways. See After Treatment for Laryngeal and Hypopharyngeal Cancer to learn more about voice restoration.

After a laryngectomy, you breathe through a tracheostomy. This is a hole (stoma) placed in the front of your neck that connects to your trachea (windpipe).

The air you breathe in and out no longer passes through your nose or mouth. This normally helps moisten, warm, and filter the air, removing dust and other particles. The air reaching your lungs will be dryer and cooler. This can irritate the lining of the tracheostomy and can cause thick or crusty mucus to build up.

It's important to learn how to take care of your stoma.

You will need to use a humidifier over the stoma as much as possible, especially right after the surgery, until your airway lining has a chance to adjust to the drier air now reaching it.

You will also need to learn how to suction out and clean your stoma to help keep your airway open. Your healthcare team can teach you how to care for and protect your stoma. This includes keeping small particles out of your windpipe and making sure water does not enter it when you shower or bathe.

It is sometimes hard to swallow well after throat surgery. This can affect how you eat. If it’s severe, you might need a permanent feeding tube.

Pharyngectomy can also lead to the development of a fistula. This is an abnormal opening between 2 areas that are not normally connected. If this happens, you may need surgery to fix it.

A very rare but serious complication of neck surgery is rupture of a carotid artery. This is the large artery on either side of the neck.

More information about surgery

For more general information about surgery as a treatment for cancer, see Cancer Surgery.

To learn about some of the side effects listed here and how to manage them, see Managing Cancer-related Side Effects.

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Developed by the American Cancer Society medical and editorial content team with medical review and contribution by the American Society of Clinical Oncology (ASCO).

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Last Revised: May 28, 2026

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